SOLOSEC is the only antibiotic that provides a complete course of treatment for bacterial vaginosis (BV) in just one day, with one oral dose.1
SOLOSEC
  • Is FDA-approved to treat BV in women.1
  • Was effective in clinical studies; most women treated with SOLOSEC needed no additional treatment for BV.2,3
  • Is rapidly absorbed by your body and goes to work quickly to treat BV.1,4
  • Keeps working in the body to treat BV for several days after one dose.1,4
The American College of Obstetricians and Gynecologists (ACOG) and the Centers for Disease Control and Prevention (CDC) include SOLOSEC as a treatment for BV in their official guidelines.5,6
SOLOSEC is also approved to treat trichomoniasis (trich), a common sexually transmitted infection (STI).1
SOLOSEC is also approved to treat trichomoniasis (trich), a common sexually transmitted infection (STI).1
SOLOSEC isn't a pill, gel, or cream. It's different1
Completing treatment with SOLOSEC is simple:

SOLOSEC helps you avoid the use of leaky intravaginal creams or gels and taking pills on multiple days.1,5,7

SOLOSEC can be taken at any time of day.1

SOLOSEC does not interfere with a common birth control pill*, condoms or diaphragms.1
*Combination oral contraceptive ethinyl estradiol and norethindrone

With SOLOSEC, you can continue to use your vaginal products (tampons).1
Completing treatment
with SOLOSEC is simple:
SOLOSEC helps you avoid the use of leaky intravaginal creams or gels and taking pills on multiple days.1,5,7
SOLOSEC can be taken at any time of day.1
SOLOSEC does not interfere with a common birth control pill*, condoms or diaphragms.1
*Combination oral contraceptive ethinyl estradiol and norethindrone
With SOLOSEC, you can continue to use your vaginal products (tampons).1
Complete Treatment with One Oral Dose
SOLOSEC 2 g
One dose, ONCE
Another common medication for trich
14 Doses, 2x per day for 7 days
With only one oral dose to remember, SOLOSEC makes it simpler to complete treatment and get back to your routine.1
The entire SOLOSEC packet is taken sprinkled over applesauce, pudding, or yogurt and eaten within 30 minutes.1
References:
1. SOLOSEC [Prescribing Information]. Evofem Biosciences, Inc.: San Diego, CA; October 2024. 2. Schwebke JR, Morgan FG Jr, Koltun W, Nyirjesy P. A phase-3, double-blind, placebo-controlled study of the effectiveness and safety of single oral doses of secnidazole 2 g for the treatment of women with bacterial vaginosis [published correction appears in Am J Obstet Gynecol 2018;219(1):110]. Am J Obstet Gynecol 2017;217(6):678.e1-678.e9. 3. Hillier SL, Nyirjesy P, Waldbaum AS, et al. Secnidazole treatment of bacterial vaginosis: a randomized controlled trial. Obstet Gynecol 2017;130(2):379-386. 4. Nyirjesy P, Schwebke JR. Secnidazole: Next generation antimicrobial agent for bacterial vaginosis treatment. Future Microbiol 2018;13:507-524. 5. American College of Obstetricians and Gynecologists. ACOG Practice Bulletin: Clinical Management Guidelines for Obstetricians-Gynecologists, Number 215. Obstet Gynecol 2020:135(1):e1-e174. 6. Workowski KA, Bachmann LH, Chan PA, et al. CDC Sexually Transmitted Diseases Treatment Guidelines, 2021. MMWR Recomm Rep 2021;70(RR-04):1-192. 7. U of Illinois-Chicago Drug Information Group. How to Use Vaginal Suppositories. Healthline.com. Updated 22 May 2017.
 

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What is SOLOSEC?

SOLOSEC® (secnidazole) 2g oral granules is a prescription medicine used to treat bacterial vaginosis in females 12 years of age and older. SOLOSEC is used to treat Trichomoniasis, a common sexually transmitted infection (STI), in people 12 years of age and older. People taking SOLOSEC for Trichomoniasis should avoid having sex until they and their sex partners are treated with the same dose and at the same time, to prevent reinfection. It is not known if SOLOSEC is safe and effective in children under 12 years of age.

How should I take SOLOSEC?

SOLOSEC is a single-dose therapy for oral use. Use SOLOSEC by sprinkling an entire packet of SOLOSEC onto applesauce, yogurt, or pudding. The entire dose should be taken at once, and finished within 30 minutes. Avoid chewing or crunching the granules. SOLOSEC should not be taken by dissolving the granules in any liquid. Avoid drinking alcohol during treatment with SOLOSEC and for 2 days (48 hours) after you take SOLOSEC.

Important Safety Information

  • You should not use SOLOSEC if you've had an allergic reaction to secnidazole, other ingredients of the formulation, or other nitroimidazole derivatives or have Cockayne syndrome.
  • Before taking SOLOSEC, tell your healthcare provider about all of your medical conditions, including if you
    • Are pregnant or plan to become pregnant.
    • Are breastfeeding or plan to breastfeed. Breastfeeding is not recommended. You should not breastfeed for 96 hours (4 days) after taking SOLOSEC.
  • Vaginal yeast infections may occur with SOLOSEC and require an antifungal treatment.
  • The most common side effects of SOLOSEC include headache, nausea, vomiting, diarrhea, abdominal pain, vaginal itching and a bad, bitter or metallic taste in your mouth (dysgeusia).
  • Take SOLOSEC exactly as your healthcare provider tells you to. Do not take SOLOSEC more often than it is prescribed.

Call your doctor for medical advice on side effects. You are encouraged to report suspected side effects of prescription drugs to FDA at www.fda.gov/MedWatch also at 1-800-FDA-1088 or contact Evofem Biosciences, Inc. at 1-833-EVFMBIO (1-833-383-6246).

Please see full prescribing information for SOLOSEC, available here.

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